Contains in 1 ml as an active ingredient 25 mg of ketoprofen, and as excipients L-arginine, benzyl alcohol, citric acid and water for injection.
Ketoprofen, which is part of Flexoprofen, has anti-inflammatory, analgesic and antipyretic effects, is effective for the treatment of acute, subacute and chronic inflammation, accompanied by a symptom of pain. The mechanism of action of ketoprofen is to suppress the synthesis of prostaglandins, by disrupting the metabolism of arachidonic acid.
With intramuscular administration of the drug, the maximum concentration of ketoprofen in the blood plasma is noted after 30 minutes. The bioavailability of ketoprofen varies from 85% to 100%, depending on the type of animal. Ketoprofen from the body is excreted mainly through the kidneys.
The drug is used to treat inflammatory diseases of the musculoskeletal system and as an anesthetic and antipyretic in dogs, cats, sport horses and calves.
Dosage and method of use
Flexoprofen 2.5% is used to treat inflammatory diseases of the musculoskeletal system (arthritis, arthrosis, sprains, edema, herniation of intervertebral discs, synovitis, tenosynovitis, etc.), pain syndrome of various etiologies (traumatic and postoperative pain, colic), as well as hyperthermia in dogs, cats, sport horses and calves. Dosage and administration:
Dogs, cats: subcutaneously, intramuscularly,
intravenously at a dose of 2 mg / kg animal weight (for ketoprofen), 1 time per day, for 1-5 days.
Sports horses: intravenously at a dose of 2.2 mg / kg of animal weight (for ketoprof-nu), 1 time per day, for 1-5 days.
Calves: intravenously or intramuscularly at a dose of 3 mg / kg animal mass (according to keto-profen), 1 time per day, for 1-5 days.
Contraindications to the use of Flexoprofen 2.5% are allergies to ketoprofen and other components of the drug, gastric and duodenal ulcer, hemorrhagic syndrome, severe hepatic and renal failure, pregnancy.
Flexoprofen 2.5% is not recommended for use in conjunction with other non-steroidal anti-inflammatory drugs, glucocorticoids, anticoagulants and diuretics. Do not mix with other drugs in the same syringe.
At recommended doses, Flexoprofen 2.5% does not cause complications in animals.
When working with Flexoprofen 2.5%, you should follow the general rules of personal hygiene and safety precautions provided for when working with drugs.
Release form: Flexoprofen 2.5% is packaged in 5, 10, 20, 30, 50, 100, 200 and 250 ml vials of dark glass of the appropriate capacity.
"Flexoprofen" (Flexoprofen) is an anti-inflammatory nonsteroidal medicine, injection solution, produced in three variations of concentration - 2.5%, 5%, 10%. Accordingly, in 1 ml of this product contains 25, 50 and 100 mg of ketoprofen. Auxiliary elements are citric acid, benzyl alcohol, L-arginine, distilled water for injection.
Instructions to the "Flexoprofen" for cats indicates that it looks like a colorless or slightly yellowish solution. It is packaged in dark glass bottles (ml):
Each bottle on the territory of the Russian Federation necessarily has a label with information in Russian:
- Manufacturer, its trademark and legal address.
- The name of the drug itself, the names of the active substances.
- The volume of the drug.
- Factory series, date of manufacture.
- Storage conditions.
- Period of validity.
- Inscriptions "For animals", "Sterile", "For injection".
"Flexoprofen" for cats is supplied with instructions for use without fail.
Possible analogues of the drug: "Ainil" (1%), "Ketoquin" (1% and 10%), "Ketofen" (1%), "Ketoject". We indicate in the instructions for "Flexoprofen" for cats price (average values):
- 10% drug (50 ml) - within 1000 rubles.
- 5% drug (50 ml) - within 800 rubles.
- 2.5% drug (10 ml) - within 300-500 rubles.
Pharmacological properties of drugs
The active component of the drug, as we have already mentioned, is ketaprofen. It has the following properties:
- Pain reliever
According to the instructions, reviews of "Flexoprofen" for cats, the drug is successfully used to treat the entire range of inflammations - acute, chronic, subacute, accompanied by pain. The mechanism of action of ketaprofen is as follows: the substance disrupts the metabolism of arachidonic acid, which in turn inhibits the formation of prostaglandins.
When i / m administration of the drug its highest concentration in the blood plasma is noticeable after half an hour. Bioavailability for the body: 85-100% (depending on the type of animal). Displays medication through the kidneys.
Instructions to "Flexoprofen" for cats indicates that the tool is close to low-hazard (4th grade according to GOST 12.1.007-76). If the recommended dosage is observed, then it does not have a sensitizing effect on the patient.
Indications for use
The instruction to "Flexoprofen" for cats provides the following indications for use:
- Inflammations of the musculoskeletal system: arthritis, edema, dislocations, synovitis, herniated intervertebral discs, arthrosis, tendosynovitis and so on.
- Pain syndrome of various origins, incl. colic, trauma, postoperative syndrome.
Application and dosage
Instructions to "Flexoprofen" for cats, dogs and other animals in the field of application and dosage presented in this table.
At observance of the specified dosages use of the drug does not cause complications. Overdose leads to loss of appetite, vomiting, diarrhea. In this case, discontinue treatment immediately. Avoid skipping injections - this may reduce the effectiveness of therapy. If the dose of the drug was not introduced on time, it is not necessary to introduce a double one - only return to the previous treatment regimen faster.
Contraindications, the use of other drugs
Contraindications to the introduction of "Flexoprofen" the following:
- Individual intolerance of both ketoprofen itself and auxiliary substances.
- Hemorrhagic syndrome.
- Both kidney and liver failure.
- Duodenal ulcer, stomach.
It is not recommended to mix in the same syringe with other dosage forms. It is also forbidden to combine with taking the following drugs:
- Nonsteroidal anti-inflammatory drugs.
Storage of the drug should be carried out with caution - refers to list B:
- Dry place, protected from direct sunlight.
- Storage temperature - 5-25 degrees.
- The maximum shelf life is 3 years. After its expiration, the use of the drug is prohibited.
The specific conditions for using this drug are:
- When administering an injection to an animal, it is important to follow the prescriptions of personal hygiene and safety procedures for working with medicines. To eat, liquid, smoke at this time is strictly prohibited! After the procedure, be sure to wash your hands with soap and water.
- If the solution gets on your skin or mucous membranes, wash them with plenty of water. If there are incomprehensible reactions, especially if you are hypersensitive to at least one of the components of the drug, you should contact the health facility as soon as possible.
- Do not use vials from the funds for domestic purposes.
- Do not allow access to the medicine to children.
"Flexoprofen", which has more expensive counterparts, is an excellent remedy with a small number of contraindications, low-risk in case of overdose. And, as we have seen, it has a large range of indications for use, suitable not only for cats and dogs, but also for a number of other animals.
Composition, release form, packaging
The main active ingredient - ketoprofen, additionally contains L-arginine, benzene alcohol, citric acid and water for injection. Colorless 2.5% solution is produced in dark glass containers with volumes of 5, 10, 20, 30, 50, 100, 200 and 250 ml, in a carton package there is an insert with instructions.
Adults and calves: in a vein or muscle, 3 mg / kg once a day, about five days.
Pigs are injected into a muscle at the rate of 3 mg / kg of body weight, one dose per day, and duration from five days to a week.
Precautions and special instructions
It is not recommended to skip the medication, you will have to renew the scheme again. It is not necessary to allow joint reception with other anti-inflammatory agents, with diuretic and blood thinning, steroid hormonal agents. You can not mix in the same syringe with other drugs. During contact with the drug, you should not drink or eat food; after contact, wash hands thoroughly; in case of contact with skin or eyes, rinse with clean water.
Slaughter of farm animals for meat is allowed five days after the last dose of the agent; milk can be consumed without restrictions.
Contraindications, overdose symptoms and side effects
Among the contraindications are the following diseases:
- gastrointestinal ulcer,
- renal and hepatic failure,
- hemorrhagic syndrome
- von Willebrand disease (in dogs).
Shelf life and storage conditions
The medication is kept out of the reach of children and animals, away from food and feed. When stored on the drug should not get sunlight, the permissible temperature from 0 ° C to +25 ° C. In a closed container can be stored for up to three years.
“Flexopropen” received high reviews from pet owners and owners of farm cattle. However, remember that the unauthorized appointment of a medical product is unacceptable, you can cause an even greater harm to the sick animal.
Composition and release form
The manufacturer of the drug is the Russian company VIK - Animal Health. The price of the medicine depends on the volume of the bottle. A 10 ml bottle will cost 300-350 rubles, and a 50 ml bottle costs about 700 rubles. Since the product is manufactured in Russia, it can be purchased at any veterinary pharmacy.
Flexoprofen for dogs is available as a solution for injection. Often, the liquid is clear, but sometimes it can become yellow. Means is packaged in glass bottles with a volume of from 5 to 100 ml. The medicine bottles are sealed with rubber stoppers and covered with thin metal caps.
The main active ingredient is ketoprofen. In veterinary pharmacies, you can find products with different concentrations of this substance: 2.5%, 5% and 10%.
In addition to ketoprofen, Flexoprofen includes:
- citric acid (pH 6.0-7.0),
- purified water,
- amino acid L-arginine,
- alcohol (gasoline).
Flexoprofen is a non-steroidal injectable drug that is widely used in veterinary medicine. It relieves pain well, reduces temperature, reduces swelling, relieves small inflammations.
This action is possible due to the main active component (ketoprofen), which temporarily blocks the production of simple cold tea. The drug starts its full effect in 25-35 minutes after administration.
The tool does not accumulate in the body, is not addictive. Excreted through the kidneys.
Method of application and selection of dosage
Flexoprofen dosage for dogs is calculated simply, for 1 kilogram of weight 2 mg of active substance is required. With a dog's weight of 5 kg, the required dose is 10 mg, that is, 0.2 ml of 5% Flexoprofen or 0.4 ml of 2.5%. You need to take medicine at the same time, preferably in the morning.
Flexoprofen should be administered (intramuscularly or intravenously) to a sick pet once a day until the heat / inflammation has completely disappeared.
You can give the drug no more than five days in a row, if after this period the symptoms have not passed, you should consult a doctor. The exact treatment regimen should make the vet.
Side effects and contraindications
In case of inappropriate medication side effects occur:
- vomiting (in rare cases).
You can not prick the substance if:
- the dog has a gastric or duodenal ulcer,
- female wears puppies
- the animal is diagnosed with hemorrhagic syndrome,
- The pet has serious kidney problems (renal failure, etc.).
If the topic of contraindications is relevant for you, but you do not want to use one of the Flexoprofen analogues for dogs, then it is better to contact the veterinarian and ask how much and how much to give the medicine to the sick animal.
If you take into account contraindications and clearly follow the instructions for use, the risk of an overdose is very small. But to understand what can happen to an animal, you need to know the symptoms of an overdose. The main features include:
- refusal to eat (sometimes water),
If you notice at least a few of these symptoms, you need to immediately stop taking the medicine and call the veterinarian. Until he arrives, make sure that the dog drinks water, do not make noise near it and ventilate the room in which it is located.
Interaction with other drugs
Flexoprofen should not be taken in combination with other medications, avoid sharing with:
- nonsteroidal anti-inflammatory drugs
- blood thinners,
Terms and conditions of storage
The drug is valid for three years, but the tool can deteriorate earlier if stored incorrectly. We advise you to adhere to the following storage rules:
- Air temperature should not be above 25 and below 5 degrees.
- Humidity is not more than 75%.
- On the drug should not get direct sunlight.
- Next to the medicine should not be food or household chemicals.
If Flexoprofen was not on sale, you can replace it with one of the following analogues.
The drug company "Api-San" (Russia). Available in the form of a solution for injection. It copes well with fever and inflammations. Not addictive. Odorless. The main active ingredient is ketoprofen. It begins to affect the body 40 minutes after the injection. Price - 250-300 rubles. (100 ml.).
Antipyretic drug for dogs. Helps relieve swelling and inflammation, normalizes temperature. The main active ingredient is ketoprofen. Manufacturing company INDUSTRIAL VETERINARIA S.A., Spain. Price - 700 rubles. (100 ml).
Quality remedy that fights fever and inflammation in dogs, cats, cattle and horses. Form release - solution for injection. It is packaged in bottles from 10 to 250 ml. The main active ingredient is ketoprofen. Manufacturer - Areal Medical, Russia. Price - 300 rubles. (100 ml.).
Before using any of these drugs, it is better to consult a veterinarian, because the main component of them is the same as that of Flexoprofen, but the composition is slightly different. This means that they can cause allergies or other unpleasant symptoms that Flexoprofen did not cause.
“Our Zika had problems with his joints, which made him very sluggish, did not want to eat, and sometimes even got up. At first I bought, on the advice of a pharmacist, Hondrotron, but he only aggravated the problem. Went to the vet, he prescribed Flexoprofen. After two days of using this tool, the dog "came to life." I started to run, I normally eat and even asked to go outside. There were no side effects. Definitely recommended! ”